| Catalog #: |
SGA20357
|
| Product Name : |
RTN3 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
IHC,ELISA |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of RTN3 expressed in E. Coli. |
| Host : |
Mouse IgG2a |
| Antibody Type : |
Primary antibody |
| Swissprot : |
O95197 |
| Clone # : |
10A8 |
| WB Predicted band size : |
113kDa |
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
HAP; ASYIP; NSPL2; NSPLII; RTN3-A1 |
| Background : |
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms. |
| Image : |
|
