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Monoclonal Antibody
Catalog #:

SGA20349

Product Name : SOD1 Monoclonal Antibody
Size : 100ul
Price : $375
Applications : WB,ICC,FCM,ELISA
Reactivity : Human,Mouse
Immunogen : Purified recombinant fragment of human SOD1 expressed in E. Coli.
Host : Mouse IgG1
Antibody Type : Primary antibody
Swissprot : P00441
Clone # : 6F5
WB Predicted band size : 18kDa
Data sheet :
Formulation : Ascitic fluid containing 0.03% sodium azide.
Storage : Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Aliases : ALS; SOD; ALS1; IPOA; homodimer
Background : SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
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