| Catalog #: |
SGA20346
|
| Product Name : |
CD18 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
ICC,ELISA |
| Reactivity : |
Human,Mouse |
| Immunogen : |
Purified recombinant fragment of CD18 expressed in E. Coli. |
| Host : |
Mouse IgG2b |
| Antibody Type : |
Primary antibody |
| Swissprot : |
P05107 |
| Clone # : |
10E12 |
| WB Predicted band size : |
85kDa |
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
LAD; MF17; LCAMB; LFA-1; ITGB2 |
| Background : |
CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
| Image : |
|
