| Catalog #: |
SGA20302
|
| Product Name : |
CHIT1 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
ELISA |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Primary antibody |
| Swissprot : |
Q13231 |
| Clone # : |
1D9G2 |
| WB Predicted band size : |
52kDa |
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
Chitotriosidase;CHI3; CHIT; FLJ00314; MGC125322; CHIT1 |
| Background : |
CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. |
| Image : |
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