Catalog #: |
SGA20265
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Product Name : |
NCOR1 Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
ELISA,IHC |
Reactivity : |
Human |
Immunogen : |
Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli. |
Host : |
Mouse IgG1 |
Antibody Type : |
Primary antibody |
Swissprot : |
O75376 |
Clone # : |
7A7A9 |
WB Predicted band size : |
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Data sheet : |
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Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
N-CoR; TRAC1; hN-CoR |
Background : |
NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. |
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