| Catalog #: |
SGA20261
|
| Product Name : |
EP300 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
ELISA |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of EP300 expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Primary antibody |
| Swissprot : |
Q09472 |
| Clone # : |
7D8A6 |
| WB Predicted band size : |
|
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
p300; KAT3B |
| Background : |
EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
| Image : |
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