| Catalog #: |
SGA20260
|
| Product Name : |
HDAC3 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
IHC |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Primary antibody |
| Swissprot : |
O15379 |
| Clone # : |
3A7B5 |
| WB Predicted band size : |
48.8kDa |
| Data sheet : |
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| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
HD3; RPD3; RPD3-2 |
| Background : |
HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Image : |
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