Catalog #: |
SGA20241
|
Product Name : |
PARL Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
ELISA |
Reactivity : |
Human |
Immunogen : |
Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli. |
Host : |
Mouse IgG2b |
Antibody Type : |
Primary antibody |
Swissprot : |
Q9H300 |
Clone # : |
8C4B2 |
WB Predicted band size : |
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Data sheet : |
|
Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
PSARL; PSARL1; RHBDS1 |
Background : |
PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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