| Catalog #: |
SGA20235
|
| Product Name : |
MAP4K4 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
ELISA |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Primary antibody |
| Swissprot : |
O95819 |
| Clone # : |
3C7B5 |
| WB Predicted band size : |
|
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
HGK; NIK |
| Background : |
MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Image : |
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