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Monoclonal Antibody
Catalog #:

SGA20208

Product Name : Tyro3 Monoclonal Antibody
Size : 100ul
Price : $375
Applications : ICC
Reactivity : Human
Immunogen : Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
Host : Mouse IgG1
Antibody Type : Primary antibody
Swissprot : Q06418
Clone # : 6D6F10
WB Predicted band size :
Data sheet :
Formulation : Ascitic fluid containing 0.03% sodium azide.
Storage : Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Aliases : BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467
Background : Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
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