| Catalog #: |
SGA20200
|
| Product Name : |
SRC Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
WB |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli. |
| Host : |
Mouse IgG2b |
| Antibody Type : |
Primary antibody |
| Swissprot : |
P12931 |
| Clone # : |
4F1E8 |
| WB Predicted band size : |
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| Data sheet : |
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| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
ASV; SRC1; c-SRC; p60-Src |
| Background : |
SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
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