Catalog #: |
SGA20197
|
Product Name : |
FBLN5 Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
IHC |
Reactivity : |
Human |
Immunogen : |
Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli. |
Host : |
Mouse IgG1 |
Antibody Type : |
Primary antibody |
Swissprot : |
Q9UBX5 |
Clone # : |
1G6A4 |
WB Predicted band size : |
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Data sheet : |
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Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
EVEC; UP50; ARMD3; DANCE |
Background : |
FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. |
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