Catalog #: |
SGA20191
|
Product Name : |
APOA1 Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
WB |
Reactivity : |
Human |
Immunogen : |
Purified recombinant fragment of human APOA1 expressed in E. Coli. |
Host : |
Mouse IgG1 |
Antibody Type : |
Primary antibody |
Swissprot : |
P02647 |
Clone # : |
5F4F5 |
WB Predicted band size : |
25kDa |
Data sheet : |
|
Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
MGC117399 |
Background : |
APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. |
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