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Antibody
Catalog #:

SGA20176

Product Name : Survivin Monoclonal Antibody
Size : 100ul
Price : $375
Applications : ELISA
Reactivity : Human
Immunogen : Purified recombinant fragment of Survivin expressed in E. Coli.
Host : Mouse IgG1
Antibody Type : Primary antibody
Swissprot : O15392
Clone # : 2H5H2
WB Predicted band size :
Data sheet :
Formulation : Ascitic fluid containing 0.03% sodium azide.
Storage : Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Aliases : API4; EPR-1; BIRC5
Background : Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene\'s expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
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