Catalog #: |
SGA20163
|
Product Name : |
CD20 Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
IHC,ICC |
Reactivity : |
Human |
Immunogen : |
Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH. |
Host : |
Mouse IgG |
Antibody Type : |
Primary antibody |
Swissprot : |
P11836 |
Clone # : |
3E9D3C1G3 |
WB Predicted band size : |
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Data sheet : |
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Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1 |
Background : |
CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1. |
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