| Catalog #: |
SGA20127
|
| Product Name : |
HER-2 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
IHC |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of HER-2 expressed in E. Coli. |
| Host : |
Mouse IgG2b |
| Antibody Type : |
Monoclonal Antibody |
| Swissprot : |
P04626 |
| Clone # : |
9B9D8 |
| WB Predicted band size : |
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| Data sheet : |
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| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
HER-2, C-erB-2, erbB-2 |
| Background : |
The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis |
| Image : |
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