| Catalog #: |
SGA20121
|
| Product Name : |
C-Kit Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
IHC |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of C-kit expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Monoclonal Antibody |
| Swissprot : |
P10721 |
| Clone # : |
8D7 |
| WB Predicted band size : |
145kDa |
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
PBT; SCFR; C-Kit; CD117; KIT |
| Background : |
C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. |
| Image : |
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