Catalog #: |
SGA20119
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Product Name : |
S100A1 Monoclonal Antibody |
Size : |
100ul |
Price : |
$375 |
Applications : |
IHC |
Reactivity : |
Human |
Immunogen : |
Purified recombinant fragment of S100A1 expressed in E. Coli. |
Host : |
Mouse IgG1 |
Antibody Type : |
Monoclonal Antibody |
Swissprot : |
P23297 |
Clone # : |
2C8B8 |
WB Predicted band size : |
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Data sheet : |
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Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Aliases : |
S100; S100A; S100-alpha; S100A1 |
Background : |
S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |
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