| Catalog #: |
SGA20094
|
| Product Name : |
Desmin Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
WB,IHC |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of Desmin expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Monoclonal Antibody |
| Swissprot : |
P17661 |
| Clone # : |
10H7D2 |
| WB Predicted band size : |
|
| Data sheet : |
|
| Formulation : |
Purified antibody in PBS containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
Desmin |
| Background : |
Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response. |
| Image : |
|
