| Catalog #: |
SGA20063
|
| Product Name : |
EphB6 Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
WB,IHC |
| Reactivity : |
Human |
| Immunogen : |
Purified recombinant fragment of EphB6 expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Monoclonal Antibody |
| Swissprot : |
O15197 |
| Clone # : |
8E7H12 |
| WB Predicted band size : |
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| Data sheet : |
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| Formulation : |
Purified antibody in PBS containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
HEP; MGC129910; MGC129911 |
| Background : |
EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition. |
| Image : |
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