| Catalog #: |
SGA20048
|
| Product Name : |
Mouse TUG Monoclonal Antibody |
| Size : |
100ul |
| Price : |
$375 |
| Applications : |
WB |
| Reactivity : |
Mouse |
| Immunogen : |
Purified recombinant fragment of TUG expressed in E. Coli. |
| Host : |
Mouse IgG1 |
| Antibody Type : |
Monoclonal Antibody |
| Swissprot : |
Q9BZE9 |
| Clone # : |
4A11A6G11 |
| WB Predicted band size : |
|
| Data sheet : |
|
| Formulation : |
Ascitic fluid containing 0.03% sodium azide. |
| Storage : |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Aliases : |
ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9 |
| Background : |
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin. |
| Image : |
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